1-Acetyl-4-(4-hydroxyphenyl)piperazine side chain of Ketoconazole
ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate
CAS: 67914-99-2
Molecular Formula: C13H18N2O3
1-Acetyl-4-(4-hydroxyphenyl)piperazine side chain of Ketoconazole - Names and Identifiers
1-Acetyl-4-(4-hydroxyphenyl)piperazine side chain of Ketoconazole - Physico-chemical Properties
| Molecular Formula | C13H18N2O3 |
| Molar Mass | 250.29 |
| Density | 1.219g/cm3 |
| Boling Point | 428.9°C at 760 mmHg |
| Flash Point | 213.2°C |
| Vapor Presure | 5.83E-08mmHg at 25°C |
| Refractive Index | 1.571 |
1-Acetyl-4-(4-hydroxyphenyl)piperazine side chain of Ketoconazole - Introduction
Ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate is an organic compound with the chemical formula C17H22N2O3.
Properties: It is a solid with white or off-white crystallinity and an organic acid ester and piperazine structural group. It is soluble in some organic solvents at room temperature, such as ethanol and dimethyl subunit. Its melting point is about 135-137°C.
Purpose: ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate is often used as an intermediate in organic synthesis. It can be used to synthesize some bioactive compounds, such as antitumor agents, antidepressants and so on. In addition, it can also be used in the field of pharmaceutical research and medicine.
preparation method: ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate can be synthesized by esterification of piperazine with ethyl 4-hydroxybenzoate. The specific synthesis step is to react piperazine with ethyl 4-hydroxybenzoate in the presence of an acid catalyst to produce ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate.
Safety information: Due to the lack of relevant toxicity and safety data, ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate needs to be handled and used with caution. Wear appropriate personal protective equipment at the time of use and operate in a well-ventilated area. In case of accidental contact or inhalation, seek medical attention immediately.
Properties: It is a solid with white or off-white crystallinity and an organic acid ester and piperazine structural group. It is soluble in some organic solvents at room temperature, such as ethanol and dimethyl subunit. Its melting point is about 135-137°C.
Purpose: ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate is often used as an intermediate in organic synthesis. It can be used to synthesize some bioactive compounds, such as antitumor agents, antidepressants and so on. In addition, it can also be used in the field of pharmaceutical research and medicine.
preparation method: ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate can be synthesized by esterification of piperazine with ethyl 4-hydroxybenzoate. The specific synthesis step is to react piperazine with ethyl 4-hydroxybenzoate in the presence of an acid catalyst to produce ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate.
Safety information: Due to the lack of relevant toxicity and safety data, ethyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate needs to be handled and used with caution. Wear appropriate personal protective equipment at the time of use and operate in a well-ventilated area. In case of accidental contact or inhalation, seek medical attention immediately.
Last Update：2024-04-09 19:05:51
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Product Name: Ketoconazole Impurity 28 Visit Supplier Webpage Request for quotationCAS: 67914-99-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
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